The flexible electrochemical methadone sensor based on gold nanoparticles and over-oxidized poly(thiophene) modified carbon cloth electrode
Paper ID : 1650-ICNS
Habib Razmi *1, Zeynab Khorablou2, Faezeh Shahdost-fard3
1Department of Chemistry, Faculty of Basic Sciences, Azarbaijan Shahid Madani University,
2Department of Chemistry, Faculty of Basic Sciences, Azarbaijan Shahid Madani University
3Chemistry Department, Sharif University of Technology, Tehran, Iran
In this study, a carbon cloth (CC) composite electrode modified by gold nanoparticles (Au NPs) and over-oxidized poly(thiophene) (p(Thp)–Ox) was prepared and applied to the detection of methadone (MET) in biological fluids. The flexible Ox–p(Thp) / Au NPs/ CC integrated electrode increased the oxidation peak current of MET 10 times according to bare CC. Oxidation peak current value of MET linearly increased with the concentration of MET in the ranges of 0.049–9.9 μM and 9.9–29.1 μM with a limit of detection of 14 nM (S/N=3). Excellent recovery results were obtained for determination of MET in spiked human blood plasma and urine samples at the modified electrode.
Methadone, Carbon cloth, Electrochemical sensor, Gold nanoparticles, poly(thiophene)
Status : Abstract Accepted (Poster Presentation)