Detection of aqueous glycine by Quartz Crystal Microbalance
Paper ID : 1647-ICNS
Authors:
Marzieh Sadat Hosseini1, Azam Iraji Zad *2, Manouchehr Vosoughi3, Asadollah Kalantarian4
1Institute for Nanoscience and Nanotechnology, Sharif University of technology
2Institute for Nanoscience and Nanotechnology, Sharif University of Technology Department of Physics, Sharif University of Technology
3Sharif University of Technology
4Institute for Nanoscience and Nanotechnology (INST), Sharif University of Technology, Tehran, IRAN
Abstract:
In this work we developed A quartz crystal microbalance (QCM) sensor and studied it's potential to detect glycine in aqueous solution. Cellulose nanofibril (CNF) coated QCM biosensors were prepared by spin coating of CNF dispersion on quartz crystals. The prepared CNF coated QCM biosensor was characterized by scanning electron microscopy (SEM), Fourier transform infrared spectrophotometry-attenuated total reflectance (FTIR-ATR) and water contact angle (WCA). The prepared CNF coated QCMs were successfully applied for glycine detection. Different concentrations (250–1000 μg/mL) of glycine samples were studied. The frequency shifts of QCM biosensor followed in each step of the measurement. QCM sensor showed linear behaviour in the range of 250–1000 μg/m. The results showed that the QCM setup could be developed as a biosensor for glycine detection, and seems to be a suitable sensing method for detection of other biologic molecules.
Keywords:
cellulose nanofibril (CNF); QCM; biosensor; glycine
Status : Abstract Accepted (Poster Presentation)