Preparation and characterization of PLLA/PAMAM electrospun nanofibers
Paper ID : 1530-ICNS
Authors:
paniz memarian1, Atefeh Solouk *2, Zohreh Bagher3, Somaye Akbari4, Masoumeh Haghbin nazarpak5
1a Department of Biomedical Engineering, Amirkabir University of Technology, Tehran, Iran
2Department of Biomedical Engineering, Amirkabir University of Technology, Tehran, Iran
3Department of Tissue Engineering and Regenerative Medicine,Iran University of Medical Sciences, Tehran, Iran
4Department of Textile Engineering, Amirkabir University of Technology Tehran, Iran.
5New Technologies Research Center (NTRC), Amirkabir University of Technology, Tehran, Iran
Abstract:
Poly(lactic acid) (PLA) is a synthetic polyester that has shown great utility in tissue engineering. In this study, chemical modification of poly(L-lactic acid) (PLLA) electrospun nanofibrous scaffolds blending with polyamidoamine (PAMAM) in different blend ratios was performed. The result indicated that the use of polyamidoamine could enhance the hydrophilicity of PLLA by the formation of active amine groups and also decreased the diameter of the electrospun nanofibers, which could improve some limitation of PLLA electrospun nanofibers in the tissue engineering application.
Keywords:
Poly lactic acid, Dendrimer, Electrospinning, Tissue engineering
Status : Abstract Accepted (Poster Presentation)