Gold-Coated Gadolinium Oxide Nanoparticles as MRI and CT Contrast Agents
Paper ID : 1479-ICNS
Authors:
Nasrollah Tabatabaei *1, Sharmin S Kharrazi2, Mehmet Kaya3, Amirhossein Sarmadi1, Sarah Zokaasadi4
1Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
2Tehran University of Medical Sciences
3Physiology, Koc University School of Medicine, Istanbul, Turkey
4Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
Abstract:
A contrast agent (or contrast medium) is a substance used to increase the contrast of structures or fluid within the body in medical imaging. When injected into the body, contrast agents enhance and improve the quality of the medical image. This allows the radiologist to more accurately report on how your body is working and whether there is any disease or abnormality present. Gadolinium oxide is a paramagnetic element that shortens T1 and therefore it has the ability to enhance the contrast of the MRI image. Gold on the other hand has a high atomic number and it can function as a contrast agent in radiography (X-Ray). Herein, gold-coated gadolinium oxide nanostructures were synthesized to use as multimodal contrast agents.
Keywords:
Contrast Agents; Gadolinium Oxide; Gold; Nanoparticles, MRI, CT
Status : Abstract Accepted (Poster Presentation)