Nanosize Magnetic Metal-Organic Framework UiO-66 as a Catalyst Support to immobilize Copper (II): An Efficient catalyst for Cyanation of Aryl Halides
Paper ID : 1350-ICNS
Atefeh Jarahiyan Sedeh *1, mahdi Heidarian Haris1, Firouz Matloubi Moghaddam1, Ali Pourjavadi2
1Laboratory of Organic Synthesis and Natural Products, Department of Chemistry, Sharif University of Technology, Tehran, Iran
2Department of Chemistry, Sharif University of Technology, Tehran, 11365-9516, Iran
In this study, a magnetic zirconium-metal organic framework (Zr-MOF, UiO-66-NH2) was solvothermally synthesized. At first, Fe3O4@SiO2 nanoparticles were modified with acrylic acid and then UiO-66-NH2 was grown on them. In order to immobilize of copper, the Zr-MOF was functionalized by 2, 4, 6-trichloro-1, 3, 5-triazine and 5-phenyl tetrazole. The properties of the Fe3O4@modified UiO-66@Cu (II) were investigated by various techniques such as FT-IR, FESEM and EDX. The FESEM images showed particles size was around 135 nm. After that, the catalyst tested for a coupling reaction: cyanation of aryl halides and desired products were synthesized in excellent yields. The coupling of aryl halides with both electron-rich and electron-deficient substrates proceeded well to provide the corresponding benzonitriles in excellent yields. In general, electron-withdrawing substituents on the aryl ring increase the reactivity, while electron-donating substituents decrease the reactivity. It is worth to note, mild reaction condition and shorter reaction time are the advantages of using this prepared catalyst.
Nano-UiO-66; Copper catalyzed; Coupling reaction; MOF nanocomposite
Status : Abstract Accepted (Poster Presentation)