Mineralization of Nanoporous MIL-101 (Fe) Metal–Organic Framework around Biomacromolecule
Paper ID : 1333-ICNS
Reyhane Rezaee *1, maryam tohidi2, sedigheh zeinali2
1Department of Nanochemical Engineering, Faculty of Advanced Technology, University of Shiraz, Shiraz, Iran
2Department of Nanochemical Engineering, Faculty of Advanced Technologies, Shiraz University, Shiraz, Iran
Here we report a novel method, inspired by natural bio mineralization processes, which provides unprecedented protection of bio macromolecules by encapsulating them within a class of nanoporous materials termed metal-organic frameworks (MOFs). Growing MOFs around biomolecules has recently emerged as a promising method to combine natural and synthetic materials. MOFs are excellent supporting matrices due to the high encapsulation efficiency and moderate synthetic conditions. These composite biomolecule-MOF materials show promise in biomolecule capture, encapsulation, protection, controlled release, and even forensic science. Proteins, Polysaccharides, nucleic acids, and their derivatives have been used as biomimetic mineralizing agents thus far. This report demonstrated the bio mineralization process by using MIL-101 (Fe) around bio macromolecule. The formation of the bio composite was verified by scanning electron microscopy (SEM) and X-Ray diffraction (XRD). This method showed the potential and diversity of biomimetic approaches for the design, synthesis, and functionalization of new bio- Metal-organic frameworks composite materials.
Biomineralization; Biomacromolecule; Metal-organic frameworks; MIL-101 (Fe)
Status : Abstract Accepted (Poster Presentation)