Copper terephthalic matal organic frame work - multi-walled carbon nanotubes nanocomposite modified electrode for sensitive determination of levodopa
Paper ID : 1294-ICNS
Authors:
Roghaiyeh Asadpour joghani *, Amirabbas Rafati, Javad Ghodsi
Department of Physical Chemistry, Faculty of Chemistry, Bu-Ali Sina University, P.O.Box 65174, Hamedan, Iran
Abstract:
In this work glassy carbon electrode (GCE) was modified with copper terephthalic metal-organic framework- multi-walled carbon nanotubes (MWCNTs/Cu (TPA) MOF) nanocomposites and used as a simple and sensitive sensor for levodopa (LD). This method is based on LD oxidation at GCE surface modified with (MWCNTs/Cu (TPA) MOF) nanocomposites. MOF was synthesized with the hydrothermal method. The synthesized MOF was characterized by Field emission scanning electron microscopy (FESEM) and X-ray diffraction (XRD). For modification of GCE, suspension of MOF and MWCNTs in ethanol was dropped on surface of GCE. Electrochemical studies were accomplished by square wave voltammetry (SWV). The applied MOF, as a Cu-containing synthetic peroxidase enzyme, can electrocatalyze oxidation of LD on electrode surface and in incorporation with MWCNTs illustrated satisfactory synergic electrocatalytical properties which leads to sensitive detection of LD. Limit of detection (LOD), sensitivity and linear range were 2 nM, 2.26 μAμM-1 and 0.9-35 μM respectively which in comparison to other enzymatic or non-enzymatic sensors, were completely acceptable.
Keywords:
Electrochemical non-enzymatic sensor, Levodpa, copper terephthalic matal organic frame, Multi walled carbon nanotubes.
Status : Abstract Accepted (Poster Presentation)